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A member asked:
Anyone using oxaliplatin and 5-fu for colon cancer?
5 doctors weighed in across 2 answers
Yes, absolutely: 5fu (fluorouracil) based chemotherapy is the standard chemotherapy in colon cancer. Combination of 5-FU and oxaliplatin is widely used and a standard regiment of chemotherapy in colorectal cancer. A big randoomized clinical trial in colon cancer ( mosaic study) has demonstrated the overall survival benefit of using combination of 5fu (fluorouracil)/oxaliplatin in stage iii colon cancer and limited case of stage ii disease.
Answered 9/28/2016
5.9k views
Depends on stage etc: While that combination is not the standard for adjuvant chemotherapy (given after the primary cancer is removed), it has been used in clinical trials for adjuvant as well as neoadjuvant treatment (combination therapy given as first line, before removal of the primary tumor). Cancer resut is good but complications have been higher.
Answered 4/30/2012
5.9k views
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