A member asked:

I am taking prednisone for an allergic reaction to azithromycin. can i take benadryl (diphenhydramine) before i sleep? will it help with this kind of allergic reaction?

2 doctors weighed in across 2 answers
Dr. Michael Finkelstein answered

Specializes in Internal Medicine

Yes: Benadryl (diphenhydramine) will help with the allergic reaction.feel free to take the antihistamines

Answered 2/21/2020

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No answer: You left out the information needed to answer. Benadryl (diphenhydramine) may help if you have hives. If you do, there are much better antihistamines. If you want a sleeping pill, use Benadryl (diphenhydramine). DO NOT TAKE BENADRYL (diphenhydramine) IF YOU DRIVE. It is dangerous to be sleepy and drive. If you have a rash, not hives, no antihistamine will make the slightest difference.

Answered 7/21/2016

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