A member asked:

What does vincristine do?

5 doctors weighed in across 2 answers
Dr. Liawaty Ho answered

Specializes in Hematology and Oncology

Vinca alkaloid: It interferes with the growth of cancer cells and slows their spread in the body by binding to tubulin and inhibit microtubule formation in cancer cells and arresting cancer cell growth.

Answered 5/5/2012

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Dr. Michael Engel answered

Specializes in Pediatric Hematology and Oncology

Vincristine ...: Blockscell cycle progression. Vincristine is a vinca alkaloid originally purified from periwinkle. It binds tubulin and prevents microtubule elongation. As such, t blocks the mitotic spindle and causes mitotic arrest in dividing cells. Its primary side effects are neuropathic in nature, a reflection of the important structural role played by microtubules in neuronal projections, particularly axons.

Answered 6/26/2014

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Related Questions

A member asked:

How can vincristine and doxorubicin be fatal to a cell?

A doctor has provided 1 answer