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A 36-year-old member asked:

Why do they give aminophylline to some preemies?

1 doctor answer1 doctor weighed in
Dr. Michael H. T. Sia
Pediatrics 31 years experience
For apnea or prem.: Aminophylline may be preferred to enhance contractility in the diaphragm/lungs or benefit from it's bronchodilator properties.Side effects-possible decrease in cerebral blood flow & concerns re: role in the occurrence or severity of necrotizing enterocolitis. Caffeine has a wider therapeutic margin-less chance of overdosing-thus it is the preferred agent.

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Last updated Jun 18, 2012
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