A member asked:

Why do they give aminophylline to some preemies?

A doctor has provided 1 answer

For apnea or prem.: Aminophylline may be preferred to enhance contractility in the diaphragm/lungs or benefit from it's bronchodilator properties.Side effects-possible decrease in cerebral blood flow & concerns re: role in the occurrence or severity of necrotizing enterocolitis. Caffeine has a wider therapeutic margin-less chance of overdosing-thus it is the preferred agent.

Answered 6/18/2012

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