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A member asked:

How much time does it take for sickle-cell disease to cause an autosplenectomy?

A doctor has provided 1 answer
Dr. Craig MacArthur answered

Specializes in Pediatric Hematology and Oncology

Few years: Patients with homozygous sickle cell anemia (Hgb SS) auto-infarct spleens in first few years of life. Patient's with Hgb SC or sickle cell anemia with hereditary persistence of fetal hemoglobin usually maintain some degree of splenic function.

Dr Cooper agreed

Answered 10/2/2015

3.8k views

Thank
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