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A member asked:
What is the cause of sickle cell disease and trait?
A doctor has provided 1 answer
Gene mutation: Sickle cell trait is caused bu the presence of a single mutation in the beta chain of human hemoglopin a gene. A mutation in one gene on one of a person's two beta globin genes results in sickle cell trait (sa hemoglobin) while the same mutation in both of a persons genes causes sickle cell anemia. (ss hemoglobin). The term trait means a carrier for the sickle cell mutation.
Answered 10/17/2012
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Related Questions
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If you have only the sickle cell trait, can you sometimes suffer like a person who has the disease?
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If my baby is born with sickle cell disease does that mean I and her father have to have the trait?
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If one parent has the sickle cell trait and the other is normal, is it possible that their child can get the sickle disease?
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