A member asked:

Can you get serotonin syndrome with a 6,000 mg of sertraline combined with 400 mg of phenergan (promethazine) what can happen.

5 doctors weighed in across 2 answers
Dr. Paul Grin answered

Specializes in Pain Management

Possible: Sertraline maximum dose is 200 mg/day. You mentioned 6000 (?) Phenergan maximum daily dose should not exceed 75 mg. You mentioned 400mg (?) Please contact your prescribing physician for medication adjustment. I think you should check the numbers.

Answered 5/24/2014

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Dr. Robert Grieco answered

Specializes in Family Medicine

Yes: 6000 mg sertraline is 2 months worth medicine that is more then enough. I hope you are not going to do that again. It will not be fun. Please reach out for help before the pills.

Answered 5/1/2016

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