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A 32-year-old female asked:

do standard99m tc bone scans with tracer ever reveal lytic lesions of myeloma, or only ever osteoblastic lesions, and fracture? having workup for mm.

2 doctor answers2 doctors weighed in
Dr. John Miliziano
Specializes in Nuclear Medicine
Yes: A Tc bone scan is more sensitive in detecting osteoblastic lesions however can show tracer uptake in multiple myeloma. Even though myeloma lesions are typically lytic there may be enough reactive bone to take up tracer. Bone survey with X-Ray is usually used to evaluate myeloma.
Dr. Sewa Legha
Medical Oncology 50 years experience
Bone scan, not helpf: Bone lesions of myeloma do not show up on a Bone scan. So it is not a useful test when looking for bone lesions which can be seen more easily with MRI scan. Alternatively a CT scan can help in a localised spot and PET scan can also be useful in certain select situations.

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Last updated Oct 4, 2016
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