A member asked:

How can orlistat cause hepatotoxicity?

A doctor has provided 1 answer
Dr. Matt Wachsman answered

Specializes in Internal Medicine

Coincidence likely: There are reported liver toxiicty and in the test tube its toxic to liver cells. if true; Sure is rare. http://en.wikipedia.org/wiki/Orlistat#Side_effects http://www.ncbi.nlm.nih.gov/pubmed?term=%28%231%20AND%20%232%29 ON THE OTHER HAND. Fat in liver occurs with a significant amt of fat in 1/5 fat people. Gallstones, alcohol intake and other liver injurious things also associate with obesity.

Answered 5/9/2014

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