Coughing a lot fever and running nose what is the best thing for it?

Respiratory infectio: This sounds like your classic respiratory tract infection. If you are not having any shortness of breath, chest pain or trouble breathing, then i think you can wait this out a few days at home with rest, fluids (mainly water), humidity. You can also try a neti pot to clear out mucous from the sinuses. If there are any developing, worsening chest symptoms, see doctor to check for pneumonia.