A member asked:

I'm wondering are vaccines tested in double blind placebo controlled studies?

4 doctors weighed in across 3 answers

Yes: Tthis is one method used to test for vaccine efficacy.

Answered 4/11/2017

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Dr. Matt Wachsman answered

Specializes in Internal Medicine

I know about this: Yes, they need a LOT of FDA approval including 1 probably 2 double blind trials. There is the problem of blinding and it can be tricky to have a true blind.

Answered 8/10/2017

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Double blind: In this case double blind has no connection with loss of vision. It means that both the patient and the doctor do not know which one is the real medicine and such they can appreciate better its effect. For vaccines we can measure the antibodies triggered .A very high quantity (titer) is protective. So the procedure is very objective. The problem it is not the efficiency but the complications

Answered 8/10/2017

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