See answer: Good question. Both drugs are tkis and both are cyp3a4 inhibitors which have the potential to reduce the metabolism of tamsulosin and thereby the potential for an increase in tamsulosin-associated adverse side effects: dizziness, lightheadedness, drowsiness, runny/stuffy nose, or ejaculation problems being the most common. It may be that imitinib is a stronger cyp3a4 inhibitor than dasatinib.
Answered 1/17/2018
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