A member asked:

Interaction checkers warn against use of tamsulosin with imatnib, a cyp3a4 inhibitor. but dasatinib is a cyp3a4 inhibitor. why no warnings about it?

A doctor has provided 1 answer

See answer: Good question. Both drugs are tkis and both are cyp3a4 inhibitors which have the potential to reduce the metabolism of tamsulosin and thereby the potential for an increase in tamsulosin-associated adverse side effects: dizziness, lightheadedness, drowsiness, runny/stuffy nose, or ejaculation problems being the most common. It may be that imitinib is a stronger cyp3a4 inhibitor than dasatinib.

Answered 1/17/2018

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