Can hashimotos cause an ana titer of >1:1280 homogenous or is there something more going on. on meds for hypothyroidism currently.

Hashimoto thyroid: Hashimoto's is an auto immune thyroid condition indicating that your own body is attacking itself thereby leaving your unable to make the normal amounts of thyroid. This auto immune process can cause other positive auto-immune tests such as ana. I would be concerned that you are triggering these type of antibodies through food allergies. Many abd sxs though benign are signs of this process.

Yes: Yes, the presence of an autoimmune thyroid disease like hashimoto's can cause an elevated ANA titer, such as yours. Some patients in this situation never develop symptoms of other autoimmune diseases, but there is a subset of people who do. Have your doctor test you for other autoimmune antibodies such as ant ds-dna, anti-ro, and anti-la antibodies to name a few.