It varies: Zoloft ; Paxil (paroxetine) are similar medications with similar mechanism of action so you are not really starting at ground zero again. All the same, i usually have patients give the new medication 3-4 wks before deciding to change it or increase the dose. Individual response to anti-depressant medication varies quite a bit. There may be some trial ; error to find the right med for you. Hang in there.
Answered 6/13/2021
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