A member asked:

How does strep throat lead a child to post streptococcal glomerulonephritis?

4 doctors weighed in across 2 answers

Antibodies: The body makes antibodies to the strep which cross react with the kidneys and the body attacks it's own tissue when the immune system is tricked.

Answered 12/24/2014

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Immune response: After certain infections (such as strep throat), the body makes proteins called antibodies to protect us from the infection.The antibody binds to the proteins from the infecting agent (antigens) and make an immune complex (a larger protein) which can deposit in the tiny glomeruli (functional units of the kidney) and start an inflammatory process locally with resultant damage and glomerulonephritis

Answered 10/12/2015

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