Not usually...: There may be some non specific changes of inflammation in the duodenum seen on endoscopy like edema , erythema, and villous flattening, but these changes can be seen in many different diseases and are not specific to celiacs. Usually the diagnosis of celiac requires the trifecta of biopsy changes, positive ttg antibodies, and symptomatic improvement on gluten free diet.
Answered 4/10/2014
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