A member asked:

Can you have celiac disease with no symptoms and a normal upper endoscopy/pathology?

5 doctors weighed in across 2 answers
Dr. Su Fairchild answered

Specializes in Integrative Medicine

Depends: Usually not. Celiac disease is symptomatic, however, exact symptoms may vary from person to person. Some symptoms can be very subtle, such as fatigue. Pathology for celiac is not always 100% accurate if negative, but we always believe a positive result. One may have non-celiac gluten sensitivity and not be celiac. One may also have celiac genes but not be celiac.

Answered 1/25/2015

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Dr. Amy Deeken answered

Specializes in Pathology

Unlikely, but ...: Not impossible. Subclinical celiac can have few or non-traditional symptoms such as migraines, reflux, abdominal pain, ect... Celiac involvement can be patchy and skip areas, so it is possible to miss it on biopsy. Talk about celiac blood testing with you physician to completely rule out.

Answered 12/18/2014

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