My wife is on adderall. she was just put on amantadine and wellbutrin (bupropion) for chronic fatigue syndrome. will the addition of these meds. affect her adhd?

Same doctor?: These in combo do seem to increase side effect risks - especially for seizures. Ask the doctor(s) to be sure they are paying close attention. It is good that you are doing that - but they need to work w/ you too. A psychotherapist experienced w/ complex health issues may also help clarify the symptoms and hone in on a clearer DX if these are in question. I'd want to know more. Best!

May help: Each of these medications individually may help. Be cautious of the cumulative effect of multiple medications.