A 49-year-old male asked:
Disclaimer

the nsaid ketoprfen helps my osteoarthritis a lot.. but i am only 50 and worry about the long term side effects. what do you think?

4 doctor answers
Dr. Ronald Krauser
52 years experience Rheumatology
See details: There is a moderate GI risk but if you take a ppi such as Prilosec or Protonix (pantoprazole) at the same time you minimize that risk. Studies have suggested that there is no increase in cardiac risk with profens.
Answered on Jun 30, 2014
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Dr. Steven Sheskier
39 years experience Orthopedic Foot and Ankle Surgery
Get tested: Adviseable to have blood work and urine analysis after taking NSAID for > 3 months just to make sure your are not experiencing one of the low percentage side effects that can occur ( blood, liver, kidney).
Answered on Jun 10, 2014
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Dr. Qamar Khan
17 years experience Pain Management
Speak with Doctor: Usually long term use of nsaids may have effects on the kidneys, GI system and cardiovascular issues. You should speak with your doctor to make sure you are stable with your kidney function, make sure you don't have significant cardiovascular risk factors (high blood pressure or history of heart attack, stroke, etc) and make sure you don't have any GI upset issues for long term use to be safe.
Answered on Jun 10, 2014
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Dr. Jeffrey Kass
28 years experience Podiatry
Agreed, would be helpful if we knew what the arthritis was of....
Mar 29, 2014
Dr. Rashid Saba
21 years experience Geriatrics
Stomach and heart: You may run the risk of gastritis or stomach/ intestinal ulcer with long term use of this medication which is an NSAID (non steroidal anti inflammatory drug). You can use a medication like zantac (ranitidine) or Omeprazole to help protect yourself from this outcome. Keep in mind all nsaids increase your risk of heart attack/ cardiac event.
Answered on Jun 30, 2014
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Dr. Ronald Krauser
52 years experience Rheumatology
Zantac does not offer protection from NSAID gastritis in commonly used doses. Profens have not been shown to have greater cardiac risk than placebo.
Apr 3, 2014

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