What the best dose of zoloft (sertraline) for gad and depression?

There is no one best: Dose. Each person is different. Usually start with a sub-therapeutic dose of 25mg per day (to help the brain get used to it). Then titrate upwards. Most often - a dose between 50 to 200 mg is a good one. However sometimes we need to use "off -label" dosing (higher than fda recommendation) to get a better response. The ultimate dose depends on how your respond (efficacy and side effects). Be well.

Cannot say: It depends on the person, severity of symptoms, other health issues, and other meds taken. Generally, it is started at a low dose and then titrated up until effective while minimizing the side effects. There is no standard dose for gad and depression, only a range (which is broad).