A 25-year-old male asked:
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started taking zoloft (sertraline) a day ago for gad and experienced depression symptoms or sadness after first dose, initial side effects?

1 doctor answer
Dr. Rebecca Gliksman
37 years experience Internal Medicine
Depression w/ zoloft (sertraline): Let your doctor know immediately ( today). All SSRIs have a black box warning that they can cause suicidal ideation and should be stopped in that situation. Since you just started would call your doctor/see urgent care immediately in the AM and let them know of the depression before taking a second dose.
Answered on May 15, 2018
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