A member asked:

My dr just took me off 70 mg of vyvanse (lisdexamfetamine) and started me on prozac. how long do i need to wait before taking the prozac to avoid a possible interaction?

10 doctors weighed in across 4 answers
Dr. Lynne Weixel answered

Specializes in Clinical Psychology

Talk to the Doctor: These are points of information that the doctor needs to cover with you. Call the office and ask for a follow-up conversation on the last visit. You should not need to pay additional money. This is an important part of that contact. Don't stop until you understand enough to feel clear about such things as you ask. It is part of what they need to do for their own benefit as well as yours.

Answered 3/8/2016

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Dr. Alan Koenigsberg answered

Specializes in Psychiatry

Ask doctor: Vyvanse (lisdexamfetamine) is used to treat adhd, and Prozac is used for depression, two different illnesses. I'm not sure why your doctor stopped the vyvanse (lisdexamfetamine), (lisdexamfetamine) so it's very difficult to give you a clear answer. I always gently taper my patients when they are on a higher dose of medication, and 70 mgs of vyvanse (lisdexamfetamine) is a the higher dose range. I would wait several days. Talk to your doctor.

Answered 6/30/2014

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Very little: Vyvanse (lisdexamfetamine) is a stimulant and it is mostly out of your system in 24-48 hours. Also, Prozac will take several weeks to reach a steady state concentration in your body. Prozac can help anxiety and depression. This can increase your concentration and focus. Best wishes.

Answered 6/30/2014

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Depends: If these are the only medications you are on, then there is no need to impose a wait time between starting Prozac after stopping vyvanse (lisdexamfetamine). These medications are often prescribed concurrently. Prozac (fluoxetine) is considerable potential for interactions with a variety of medications. As such, ensure that your prescribers know that you are taking it to minimize potential interactions.

Answered 6/30/2014

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