A member asked:

Can you explain if it's possible to test negative for lupus but actually have it?

A doctor has provided 1 answer
Dr. Joram Seggev answered

Specializes in Internal Medicine - Allergy & Immunology

Very rarely: There is a big debate if there is sle without ana. A recent major reference on sle suggested that 98% of patients are ANA positive, leaving 2% without. However, the patients still need to have typical clinical manifestations to qualify for the diagnosis.

Answered 4/9/2016

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