Older women: It is observed that women have the lowest predicted rate of Down syndrome births at ~20 (1/1925) with a gradual risewith age.By 40 the risk reaches 1/110, 50 =1/10.Most speculate that the additive effect of lifes toxic exposures eventually add up to deminish the chances an egg can produce a normal infant.
Answered 10/4/2016
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