A member asked:

Two year old had allergic reaction to amoxicillin. dr replaced it with cefprozil. instruct on cefprozil say not to take it if allergic to penicillin?

9 doctors weighed in across 3 answers
Dr. Donald Alves answered

Specializes in Emergency Medicine

Old concern: The caution on cephalosporins if penicillin allergic dates back decades to how they were produced--there often was pcn in the cephalosporins as a byproduct. Even then, risk was rare and tiny. Now even smaller, and far better to not exclude two huge antibiotic categories at young age if don't need to. Keep an eye on child as with any medication, but should not pose a problem.

Answered 3/8/2019

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5%-10%: Chance of reacting to the cephalosporin antibiotic, if the reaction was a rash or side effect you should be ok .If it was anaphylaxis then i would be cautious. You did not say what the reaction was. Call and discuss it with your doctor who knows the specifics of your chlid's case.

Answered 9/28/2016

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Dr. Jay Park answered

Usually OK: Individuals allergic to penicillin are theoretically at risk to cross react to cephalosporins including cefprozil. However, most patients do ok.

Answered 3/18/2014

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