Yes, it is not exact: Growing lung nodules can be cancer. But the growth has to be real which means increase of more than 2-3 mm before we can get concerned. The cross sections on ct are rarely at the same level so there is one or 2 mm variation between serially done ct scans.
Answered 1/5/2019
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Yes: Ct measurements are 2 dimensional measurements of 3 dimensional objects so depending on how you choose to measure an irregularly shaped nodule will alter the resulting measurement. A 1mm change is probably within the allowed "error of measurement" for the test meaning that the test may be wrong about such a small change. At 5 mm the nodule can still be watched for growth with a later ct scan.
Answered 9/26/2016
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