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A 68-year-old female asked:

What causes the brain to shrink ?

1 doctor answer1 doctor weighed in
Dr. Walter Husar
Neurology 33 years experience
Normal Aging: As the old adage states "you begin to die the morning that you are born", one is born with the greatest amount of nerve cells and they die throughout life. This is a normal aging process.

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A 32-year-old member asked:

Can hyperosmolarity cause brain cells to shrink?

2 doctor answers7 doctors weighed in
Dr. Larry Armstrong
Neurosurgery 27 years experience
Yes: Mannitol is osmotic agent utilized to raised the serum osmolality and actually takes fluid from healthy neurons to make room for damaged neurons to swell. Another agent utilized in certain institutions is 3% nacl solution which again raises the serum osmolality for the same reason. Osmolarity is mol/kg and osmolality is mol/kg which is what is used in medicine.

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Last updated Mar 27, 2019

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