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A 48-year-old member asked:

High levels of calcium in my blood and my parathyroid hormone is off. is this cancer.?

3 doctor answers8 doctors weighed in
Dr. Liawaty Ho
Hematology and Oncology 24 years experience
Not necessarily: Primary hyperparathyroidism and malignancy are the most common causes of increase serum calcium , accounting for more than 90 percent of cases. There are ways to differentiate one to the other ( check intact pth, PTH related peptide etc) . You should see your doctor and have further blood work-up and discussion in management of the problem.
Dr. Joseph Woods
Pathology 29 years experience
Please clarify.: This can result from hyperparathyroidism, or lithium, or familial hypocalciuric hypercalcemia from normal to high levels of parathyroid hormone . Malignancy can also do this, notably lung cancer, but these cases have normal to low parathyroid hormone levels. In lung cancer release of parathyroid hormone related protein (pthrp) causes the hypercalcemia. See your doctor to find the cause.
Dr. Gurmukh Singh
Pathology 50 years experience
Insufficient informa: What do you mean by parathyroid hormone is off? Is it elevated? Elevated levels of parathyroid hormone and hypercalcemia are usually due to parathyroid adenoma, not parathyroid cancer. However, other cancers, e.g., lung cancer, multiple myeloma also cause hypercalcemia, without elevation the hormone from parathyroid gland.

Similar questions

A 48-year-old member asked:

How does parathyroid hormone lower calcium levels?

1 doctor answer1 doctor weighed in
Dr. Michael Kleerekoper
A Verified Doctoranswered
Endocrinology 52 years experience
Parathyroid hormone: Normal parathyroid hormone levels does not lower calcium levels. A low parathyroid level will lower calcium. A low calcium may increase parathyroid levels. Please discuss further with your doctor.
Last updated Dec 12, 2020


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