Can you take sertaline and cymbalta (duloxetine) together?

No not good idea: Cymbalta contains duloxetine and zoloft contains sertraline, the combination of these two drugs creates what pharmacists describe as a "major drug-drug interaction." used together, the drrugs may develop "serotonin syndrome." although rare, this is a serious condition that can result in death caused by hyperstimulation of the patient's brainstem. High risk identified with combination.