How long does it take for amitriptyline to work. i'm on 10mg 2x at night.

See answer: Depending on the reason for which you are taking amitriptyline, you may feel that it is not working for you straightaway. It can take a week or two after starting this treatment before the effect builds up and 4-6 weeks before you feel the full benefit. Starting doses are usually small to minimize side effects and if not helping, your doctor may elect to increase the dose. Stay the course.