A member asked:

Anyone ever heard of doing an incisional biopsy to diagnose skin rash?

8 doctors weighed in across 2 answers

Punch biopsy: Punch biopsy is considered the primary technique to obtain diagnostic, full-thickness skin specimens. It is performed using a circular blade or trephine attached to a pencil-like handle. The instrument is rotated down through the epidermis and dermis, and into the subcutaneous fat. The punch biopsy yields a cylindrical core of tissue that must be gently handled (usually with a needle).

Answered 4/30/2016

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Possibly: Incisional biopsy rather than punch biopsy is often necessary to diagnose inflammatory conditions that may involve the fat or deeper vessels.

Answered 6/7/2013

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