My 3 month old granddaughter has bright red cheaks that are rough. we have applied different lotions and the red comes and goes but roughness stays. ?

See your doctor: Rashes that won't resolve warrant a visit to make sure there isn't something more serous going on. Some systemic conditions can have a facial rash as one of the presenting symptoms.

Probably, eczema: Application of 1% Hydrocortisone oint or cream twice a day would be of help in terms of relieving flakiness and itching. In case of no response in a few days, consult her primary care physician.