What to do if i have had a sore throat for 3 weeks although it is not very painful at the moment but just won't go?

Medical check up.: For significant sore throat with swollen tonsils / lymph nodes – see physician ; get a strep throat test/ culture. If you have strep throat, antibiotic therapy is imperative to prevent future complications. Consider tylenol (acetaminophen) or nonsteroidal anti-inflammatory medications. Saltwater gargles: mix 1 tsp salt in 8 oz warm water – gargle with aloe vera juice twice a day. Gargle several times a day. Or.