A member asked:

How bad is it to drink alcohol on wellbutrin (bupropion) is it guarenteed to make you more depressed? i already know about the seizure risk.

6 doctors weighed in across 2 answers

Not: Guaranteed but probable. Alcohol second phase is a strong neuron-depressant, so somebody with depression may get worse.

Answered 10/6/2017

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Not a good idea.: It is not guaranteed to occur. Per Drugs.Com Drug ineteraction Checker- “Using bupropion with alcohol may increase the risk of uncommon side effects such as seizures, hallucinations, delusions, paranoia, mood and behavioral changes, depression, suicidal thoughts, anxiety, and panic attacks.” There is moderate risk. Ref: https://www.drugs.com/interactions-check.php?drug_list=1034-14582,440-203

Answered 11/28/2017

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