Have been on seroquel (quetiapine) for a long time. have had major depression for as long. can seroquel (quetiapine) be the reason for that?

Which one came first: Usually seroquel (quetiapine) is used to treat mood disorder. It is effective for major depression mostly as xr form, but as you know, no medication works for every body. The most important thing for you is to see a psychiatrist get full evaluation to determine proper diagnosis and treatment. All the best.

Seroquel (quetiapine): According to drugs.Com side effects can include: “psychosis, hallucinations, paranoid reactions, delusions, manic reaction, depersonalization, catatonic reaction, emotional lability, suicide attempt, and euphoria.” however it can also cause change in appetite, change in libido, mask-like face, apathy, weakness ; feeling tired. These types of symptoms are similar to presentations of depression.