Negative symptoms: Negative symptoms of schizophrenia or other psychotic disease are social withdrawal, lack of motivation, anhedonia, flat affect, cognitive failing. The most likely explanation is that there is some structural damage to the prefrontal cortex, affected glutamate pathways, and/or serotonin deficiencies. There is still need for research in that area.
Answered 5/8/2016
3.8k views
Dopamine: It is hypothesized that deficient transmission of dopamine at D1 receptors in the Prefrontal cortex of the brain may be a cause for negative Schizophrenia symptoms.
Answered 11/28/2017
3.7k views
8 doctors weighed in across 3 answers
2 doctors weighed in across 2 answers
A doctor has provided 1 answer
90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.
Ask your question