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Doylestown, PA
A 37-year-old female asked:

Debate: do antidepressants actually cure the brain if you stay on 6-12 mos or once off or you go back to the way you were (your brain)?

2 doctor answers5 doctors weighed in
Dr. Pamela Pappas
Psychiatry 44 years experience
Not exactly: There are studies showing that treatment of depression with ssri's is associated with increasing size of the hippocampus in the brain. This may be a marker for some healing response. Unfortunately tapering the medication too soon may result in relapse of symptoms, so the brain is clearly not "cured" by these medications. I think we have a great deal more to learn about all these factors.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Heidi Fowler
Psychiatry 27 years experience
The neuroscience is fascinating.
Feb 4, 2014
Dr. Bennett Machanic
Neurology 54 years experience
Good data regarding control and remission of symptoms, but not clearly a true "CURE". Working closely with your doctor, a decision can be made whether to continue or taper off, depending upon your needs.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Apr 3, 2021
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