Do antipsychotics & antidepressants have brain changing effects even after they are gone out of system? i feel like i not myself after they are gone

Withdrawal: Those medications do have withdrawal instructions. It may take a few weeks to get back to normal. Not every doctor follows decreasing doses so you may be more sensitive to the medication effects. Take it easy and your body will get back to its best. Should you still not feel good get a physical , labs and follow up to see if there is another reason for your symptoms.