A member asked:

Please tell me, could amitryptiline be taken indefinitely for someone who has irritable bowel syndrome/colitis?

A doctor has provided 1 answer

With supervision: The key is to have amitryptiline supervised by your doc. He/she will need to potentially monitor your heart rhythm and to counsel you against the potential side effects of the medication, which can include constipation, dry mouth, and dry eyes. However, if it is working, then it is potentially a good long-term medication. If it is not helping after 3 months, you should stop it.

Answered 9/26/2019

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