A member asked:

Can you tell me, are all brca gene mutations hereditary?

6 doctors weighed in across 2 answers
Dr. Carlos Encarnacion answered

Specializes in Medical Oncology

Good question. : The answer is no, a small number of patients with early onset breast cancer who carry a bad brca 1 or 2 mutation develop it "de novo", meaning that it started with them (after all, someone has to be the first to have it). Depending at which stage in development it happens, it may affect them to a different degree and may or may not be passed to their children. Some other cancer syndromes..

Answered 3/16/2014

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Dr. Brian Nguyen answered

Specializes in Obstetrics and Gynecology

Yes: Women w/ 2+ immediate family members w/ a hx of breast/ovarian CA at 50% chance of developing breast cancer. If you have it, get screened with CA-125 blood test, ultrasound, mammogram/MRI, usually starting at age 30. Surgery after childbearing.

Answered 5/26/2015

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