How serious is having the brca-2 gene?

BRCA-2: Having the brca-2 gene puts you at risk for breast cancer, ovarian cancer, leukemia, lymphoma, pancreatic cancer, and head and neck cancers. However, having the gene doesn't mean that you will definitely get one of these cancers. If you have two abnormal brca genes your risks is significantly increased than if you have just one abnormal brca gene.

Serious enough : That need investigation brca 2 genes are tumor suppressing genes normally repairs the damaged dna there by preventing the cancer cell formation, bra 2 mutation of this gene will loose that protection mechanism , 72% breast cancers in those families , also associated with pancreatic, & prostatic cancers, detected by genetic testing when there is strong family history.

Always serious: Women w/ 2+ immediate family members w/ a hx of breast/ovarian CA at 50% chance of developing breast cancer. If you have it, get screened with CA-125 blood test, ultrasound, mammogram/MRI, usually starting at age 30. Surgery after childbearing.