A member asked:

Can all breast cancer patients carry the brca genes?

6 doctors weighed in across 3 answers
Dr. Joseph Accurso answered

Specializes in Radiology

No!: Many patients with breast cancer have no genetic predisposition or risk for breast cancer. However, there are several genetic markers which increase the risk of developing breast cancer over a person's lifetime.

Answered 6/11/2013

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Dr. Carlos Encarnacion answered

Specializes in Medical Oncology

Yes and no: We all have the brca genes in our dna. God (or evolution, your choice) put it there with the purpose of repairing damaged dna, destroying dna that can't be repaired, and other things. When it's mutated (changed) in certain places, it does not work and leads to the development of cancer. Only a small number of breast cancer patients inherit such deleterious or "bad" mutations.

Answered 12/10/2013

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Dr. Devon Webster answered

Specializes in Medical Oncology

Yes, and no: We all have the genes named brca, but we don't all have mutations in those genes. It's the brca mutations that increase the risk for breast cancer. It turns out that 85% of breast cancers have nothing to do with the brca gene. So most patients with breast cancer do not have a brca1 or brca2 mutation. I hope that answers your question!

Answered 1/16/2014

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