Ca 19-9 is 15790.3 and cea is 168.9. does this mean cancer is spreading? does it have anything to do with platelets being 48?

Possibly: Ca19.9 elevated to that degree is often associated with cancer. Given the elevated CEA as well, these likely represent a cancer diagnosis. By themselves, these markers do not indicate cancer spread but when measured over time, their change can represent the overall cancer burden. These are not related to the low platelets but low platelets can also be a sign of cancer. Please see your doctor.

Tumor markers: Ca 19.9 and CEA are chemicals produced by cancer and are often called tumor markers. They rise and fall depending on whether cancer is growing/spreading or shrinking. Your oncologist can explain it to you if you ask. Low platelets have nothing to do with these test values.

Suggests persistence: I am going to assume these are standard units and that these are both markedly above the reference range. Most of the time, if this is done some time after treatment such as surgery is performed, this indicates that cancer persists in the body, though it says nothing about extent of spread. Your personal physicians are the best people to tell you exactly what it means for you. Best wishes.

Disease under: Remission depends on pre treatment levels , if that levels are much higher the current high levels , normal CEA is 3 ngms , CEA 0.37 units . Normal platelet count 150, 000 to 400, 000 you have most likely 48, 000 not 48 speak to the oncologist , who has more information , can give ether opinion