A member asked:

Please explain why is it that children with progeria get heart attacks or strokes so easily?

2 doctors weighed in across 2 answers

Abnormal metabolism: The accelerated aging syndrome known as progeria truly accelerates the patients aging and illness profile.Their metabolism is marked by the same abnormalities in cholesterol and fat metabolism in childhood as that seen in adult stroke and heart attack victims.Most succumb to complications of coronary heart disease as early as their teens.

Answered 1/17/2019

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Progeria: Hardening of the arteries (atherosclerosis) becomes more prominent when children with Progeria enter puberty. Rupture of athersclerotic lesions can lead to death from stroke or heart attacks.

Answered 9/7/2020

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