A member asked:

Does progeria cause heart disease?

11 doctors weighed in across 4 answers

Yes: And can usually cause death by the early teens.

Answered 8/30/2012

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Abnormal metabolism: The accelerated aging syndrome known as progeria truly accelerates the patients aging and illness profile.Their metabolism is marked by the same abnormalities in cholesterol and fat metabolism in childhood as that seen in adult stroke and heart attack victims.Most succumb to complications of coronary heart disease as early as their teens.

Answered 7/21/2014

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Unknown...: Children with progeria are genetically predisposed to premature, progressive heart disease. Death occurs almost exclusively due to widespread heart disease. As with any person suffering from heart disease, the common events for progeria children are strokes, high blood pressure, angina, enlarged heart, and heart failure, all conditions associated with aging.

Answered 8/10/2013

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Atherosclerosis: Hardening of the ateries (atherosclerosis) becomes more prominent when children with Progeria enter puberty. Rupture of athersclerotic lesions can lead to death from stroke or heart attacks.

Answered 9/7/2020

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