A member asked:

Expert opinions? which drugs should be avoided in pseudocholinesterase deficiency?

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Dr. Peter Fischer answered

Specializes in Healthcare Professional

Drugs to be aware of: Pseudocholinesterase is a blood plasma enzyme that is responsible for metabolizing certain medications. The most important drug to avoid is succinylcholine --a muscle relaxant used to facilitate intubation. Use of this medication with this deficiency will result in prolonged intubation. Other drugs to avoid are numerous: mivacurium, pilocarpine, huperzine, parathion to name a few.

Answered 4/26/2018

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