Expert opinions? which is more sedating mirtazapine or amitryptaline?

Roughly equal: This kind of question is hard to answer, as it depends on the dosage of each. Mirtazepine (brand name remeron) is probably better tolerated overall, although it's well-known to cause weight gain. Amitriptyline (brand name Elavil (amitriptyline) ; others) has more dry mouth, constipation, ; orthostasis (dizziness when standing), but can be quite effective if these aren't a problem for an individual patient.