A member asked:

Tomorrow is my first rheumatologist appointment, can aperson have autoimmune disease based on positive ana titer320 and negative4 all ab specific tests?

3 doctors weighed in across 2 answers
Dr. Victor Bonuel answered

Specializes in Internal Medicine

Not necessarily.: Check out this link. Best wishes! http://www.Rheumatology.Org/practice/clinical/patients/diseases_and_conditions/antinuclear_antibodies_(ana)/.

Answered 1/3/2014

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Yes: Many individuals with lupus or related autoimmune diseases will have an ANA as the only positive autoantibody.

Answered 6/10/2014

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