Is encephalitis a complication of lupus?

Rarely: Lupus can affect almost any organ system in severe cases. This would be a medical emergency that would require hospitalization with a team approach of experienced physicians including a rheumatologist, neurologist and infectious disease specialist.

Vasculitis: Lupus is an immune disorder that can affect vascular structures of the brain. Many cases will have abnormal findings on spinal fluid that suggest inflammation. Because no bacteria is found, it may be considered as a form of encephalitis. It is more likely a form of immune mediated vasculitis. However, lupus also affects the body's response to infection resulting in encephalitis.