A 47-year-old member asked:
Do abnormal chromosomes cause cancer?
1 doctor answer
Dr. Andrew Turrisi answered
46 years experience in Radiation Oncology
Yes. But all: Chromosomal abnormalities are not equal. Some during development are lethal and cause of sponaneous abortion (fetal demise), others cause developmental sydromes, trisomy 21 and down syndrome; trisomy 18 and edwards syndrome. The bcr-abl translocation causes cml. Many cancers have losses or gains of unkown significance.
Answered on Apr 3, 2012
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